General Discussion
Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsThe Ugly Side of Weight-Loss Drugs: Rotten Breath, Damaged Teeth, and Dry Mouth

Ozempic face is another commonly reported consequences of using these popular weight loss drugs. This is a sunken or hollowed out appearance the face can take on in people taking weight loss drugs. It can also increase signs of ageingincluding lines, wrinkles and sagging skin.
This happens because semaglutide (the active ingredient in both Ozempic and Wegovy) isnt localised to act just on the fat we want to lose. Instead, it targets all of our bodys fatincluding in the face.
But it isnt just the appearance of your face that semaglutide affects. These drugs may also affect the mouth and teeth, too. And these side-effects could potentially lead to lasting damage.
Dry mouth
Semaglutide effects the salivary glands in the mouth. It does this by reducing saliva production (hyposalivation), which can in turn lead to dry mouth (xerostomia). This means there isnt enough saliva to keep the mouth wet.
https://gizmodo.com/the-ugly-side-of-weight-loss-drugs-rotten-breath-damaged-teeth-and-dry-mouth-2000612385

The Blue Flower
(6,033 posts)I lost my appetite to such a degree that I felt weak and tired all the time. I couldn't eat more than a couple of bites of anything at a time. My doctor became concerned that I wasn't getting the nutrients I needed, so she took me off of it. I'm on insulin now and feel much better.
Freddie
(9,916 posts)A wonder drug, so far. 26 lbs down, lots more to go but I feel great. Sometimes I have to force myself to eat. Doc said balanced diet with lots of protein and water. My daughter was on Wegovy and couldnt deal with the nausea and vomiting.
hlthe2b
(110,795 posts)It doesn't just reduce hunger, but in worst-case scenarios, can result in life-threatening intestinal blockages, diabetes (new or existing) that is refractory to insulin and other drugs (extremely difficult to control), malnutrition from poor absorption of nutrients, life-threatening dehydration, biliary disease, pancreatitis, and on and on.
Yes, the weight loss can be incredibly beneficial from a cardiovascular point of view--as it can with some long-standing diabetics (albeit that is a mixed issue as discussed above) but...
"Miracle" for some. "Deadly" for others. But the worst is the non-FDA-approved compounded analogs, for which we have zero control over their exact components...
Taking it purely to lose a few pounds to look like a Hollywood "influencer" sans medical oversight may well end with you in the ER.
tanyev
(47,265 posts)Id rather experiment with intermittent fasting. I dont see me being able to do that as long as Im working, but since Im planning to quit in a few months, thats going to be at the top of my post-work to do list.
newdeal2
(3,460 posts)Yes these are possible. But they seem like they are stretching to find negatives to drive clicks.
elocs
(24,486 posts)I remember an old Twilight Zone episode that I just can't find on a search because the wrong episode ("To Serve Man" keeps coming up. But it's one where people would take a drug (?) which allowed them to eat as much as they liked without gaining weight and it worked great. The TZ fly in the ointment was that it didn't allow them to absorb any needed nutrients from the food they were eating so in reality they were starving to death while gorging themselves.
Our weight problem is the result of SAD, the Standard American Diet and we are reaping the consequences of how the big food companies say we should eat, like eating sugary cereal for breakfast each day.