From https://news.uga.edu/director-discusses-repurposing-drug-to-battle-brain-eating-amoeba/ :
Dennis Kyle, director of the Center for Tropical and Emerging Global Diseases, recently spoke with Science.org about using the drug nitroxoline to treat a rare infection of the central nervous system in a patient caused by the amoeba Balamuthia mandrillaris.
In the summer of 2021, a 54-year-old man was brought to a hospital in Northern California after an unexplained seizure. More testing eventually revealed the infection.
The medical team at the University of California, San Francisco, Medical Center went on a hunt for a cure, which led them to a study published several years ago in which researchers showed a drug originally developed in Europe to quell urinary tract infections was effective against Balamuthia in the laboratory. They moved to obtain the drug, nitroxoline, from abroad so it could be given for the first time to a Balamuthia patient.
The drug nitroxoline, which was developed years ago to combat urinary tract infections, fell into obscurity in the United States because of the development of newer, more effective drugs. The only country now producing it is China.
The 54-year-old patient referred to in the above excerpt died from the infection. The researchers experimented with number of drugs upon tissue extracted from the patient. It is discovered that the drug nitroxoline is highly effective in combating Balamuthia mandrillaris.
Subsequently, the life of a young patient in Texas was threatened by amoeba Balamuthia mandrillaris. The drug manufacturer in China shipped free dosages to Texas, with free shipping costs, to the Texas hospital treating the young patient. The dosages arrived within twenty-four hours and saved the patient's life.
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